The PPP1R10 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PPP1R10. This antibody recognizes Human, Mouse, and Rat antigen. The PPP1R10 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Function: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).
Subunit Structure: Component of the PTW/PP1 phosphatase complex, composed of PPP1R10/PNUTS, TOX4, WDR82, and PPP1CA or PPP1CB or PPP1CC. Interacts with PPP1CC. Interacts with PPP1CA, WDR82 and TOX4 (By similarity).
Post-translational Modifications: Phosphorylated on Ser-398 by PKA within the region necessary for interaction with PPP1CA